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General Anesthetic Isoflurane Modulates Inositol 1,4,5-Trisphosphate Receptor Calcium Channel Opening
BACKGROUND: Pharmacological evidence suggests that inhalational general anesthetics induce neurodegeneration in vitro and in vivo through overactivation of inositol trisphosphate receptor (InsP(3)R) Ca(2+) release channels, but it is not clear whether these effects are due to direct modulation of ch...
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| Publicado no: | Anesthesiology |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4281525/ https://ncbi.nlm.nih.gov/pubmed/24878495 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0000000000000316 |
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