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Sterol Transfer between Cyclodextrin and Membranes: Similar but Not Identical Mechanism to NPC2-Mediated Cholesterol Transfer
[Image: see text] Niemann–Pick C disease is an inherited disorder in which cholesterol and other lipids accumulate in the late endosomal/lysosomal compartment. Recently, cyclodextrins (CD) have been shown to reduce symptoms and extend lifespan in animal models of the disease. In the present studies...
Shranjeno v:
| izdano v: | Biochemistry |
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| Main Authors: | , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2011
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4281486/ https://ncbi.nlm.nih.gov/pubmed/21740003 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi200574f |
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