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Sterol Transfer between Cyclodextrin and Membranes: Similar but Not Identical Mechanism to NPC2-Mediated Cholesterol Transfer

[Image: see text] Niemann–Pick C disease is an inherited disorder in which cholesterol and other lipids accumulate in the late endosomal/lysosomal compartment. Recently, cyclodextrins (CD) have been shown to reduce symptoms and extend lifespan in animal models of the disease. In the present studies...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Biochemistry
Päätekijät: McCauliff, Leslie A., Xu, Zhi, Storch, Judith
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2011
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4281486/
https://ncbi.nlm.nih.gov/pubmed/21740003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi200574f
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