The opioid receptor pharmacology of GSK1521498 compared to other ligands with differential effects on compulsive reward-related behaviours

RATIONALE: The novel opioid receptor antagonist, GSK1421498, has been shown to attenuate reward-driven compulsive behaviours, such as stimulant drug seeking or binge eating, in animals and humans. Here, we report new data on the receptor pharmacology of GSK121498, in comparison to naltrexone, naloxo...

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Detalhes bibliográficos
Publicado no:Psychopharmacology (Berl)
Main Authors: Kelly, Eamonn, Mundell, Stuart J., Sava, Anna, Roth, Adelheid L., Felici, Antonio, Maltby, Kay, Nathan, Pradeep J., Bullmore, Edward T., Henderson, Graeme
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2014
Assuntos:
Original Investigation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4281354/
https://ncbi.nlm.nih.gov/pubmed/24973897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-014-3666-3
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