Subfamily-Specific Adaptations in the Structures of Two Penicillin-Binding Proteins from Mycobacterium tuberculosis

Beta-lactam antibiotics target penicillin-binding proteins including several enzyme classes essential for bacterial cell-wall homeostasis. To better understand the functional and inhibitor-binding specificities of penicillin-binding proteins from the pathogen, Mycobacterium tuberculosis, we carried...

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Publicat a:PLoS One
Autors principals: Prigozhin, Daniil M., Krieger, Inna V., Huizar, John P., Mavrici, Daniela, Waldo, Geoffrey S., Hung, Li-Wei, Sacchettini, James C., Terwilliger, Thomas C., Alber, Tom
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4281109/
https://ncbi.nlm.nih.gov/pubmed/25551456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0116249
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