A lysine acetyltransferase contributes to the metabolic adaptation to hypoxia in Mycobacterium tuberculosis

Upon inhibition of respiration, which occurs in hypoxic or nitric oxide-containing host microenvironments, Mycobacterium tuberculosis (Mtb) adopts a non-replicating ‘quiescent’ state and becomes relatively unresponsive to antibiotic treatment. We used comprehensive mutant fitness analysis to identif...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Cell Chem Biol
Main Authors: Rittershaus, Emily S. C., Baek, Seung-Hun, Krieger, Inna V., Nelson, Samantha J., Cheng, Yu-Shan, Nambi, Subhalaxmi, Baker, Richard E., Leszyk, John D., Shaffer, Scott A., Sacchettini, James C., Sassetti, Christopher M.
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6309504/
https://ncbi.nlm.nih.gov/pubmed/30318462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2018.09.009
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