Protective role of olesoxime against wild-type α-synuclein-induced toxicity in human neuronally differentiated SHSY-5Y cells

BACKGROUND AND PURPOSE: Parkinson's disease (PD) is usually diagnosed clinically from classical motor symptoms, while definitive diagnosis is made postmortem, based on the presence of Lewy bodies and nigral neuron cell loss. α-Synuclein (ASYN), the main protein component of Lewy bodies, clearly...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Gouarné, C, Tracz, J, Paoli, M Giraudon, Deluca, V, Seimandi, M, Tardif, G, Xilouri, M, Stefanis, L, Bordet, T, Pruss, R M
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2015
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4280980/
https://ncbi.nlm.nih.gov/pubmed/25220617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12939
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