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Inhibition of COX-2-mediated eicosanoid production plays a major role in the anti-inflammatory effects of the endocannabinoid N-docosahexaenoylethanolamine (DHEA) in macrophages

BACKGROUND AND PURPOSE: N-docosahexaenoylethanolamine (DHEA) is the ethanolamine conjugate of the long-chain polyunsaturated n-3 fatty acid docosahexaenoic (DHA; 22: 6n-3). Its concentration in animal tissues and human plasma increases when diets rich in fish or krill oil are consumed. DHEA displays...

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Detaylı Bibliyografya
Yayımlandı:Br J Pharmacol
Asıl Yazarlar: Meijerink, Jocelijn, Poland, Mieke, Balvers, Michiel G J, Plastina, Pierluigi, Lute, Carolien, Dwarkasing, Jvalini, van Norren, Klaske, Witkamp, Renger F
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Blackwell Publishing Ltd 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4280965/
https://ncbi.nlm.nih.gov/pubmed/24780080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12747
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