Age-related variations in the methylome associated with gene expression in human monocytes and T cells

Age-related variations in DNA methylation have been reported; however, the functional relevance of these differentially methylated sites (age-dMS) are unclear. Here we report potentially functional age-dMS, defined as age- and cis-gene expression-associated methylation sites (age-eMS), identified by...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Nat Commun
Κύριοι συγγραφείς: Reynolds, Lindsay M., Taylor, Jackson R., Ding, Jingzhong, Lohman, Kurt, Johnson, Craig, Siscovick, David, Burke, Gregory, Post, Wendy, Shea, Steven, Jacobs, David R., Stunnenberg, Hendrik, Kritchevsky, Stephen B., Hoeschele, Ina, McCall, Charles E., Herrington, David, Tracy, Russell P., Liu, Yongmei
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 2014
Θέματα:
Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4280798/
https://ncbi.nlm.nih.gov/pubmed/25404168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms6366
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