Blood monocyte transcriptome and epigenome analyses reveal loci associated with human atherosclerosis

Little is known regarding the epigenetic basis of atherosclerosis. Here we present the CD14+ blood monocyte transcriptome and epigenome signatures associated with human atherosclerosis. The transcriptome signature includes transcription coactivator, ARID5B, which is known to form a chromatin derepre...

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Vydáno v:Nat Commun
Hlavní autoři: Liu, Yongmei, Reynolds, Lindsay M., Ding, Jingzhong, Hou, Li, Lohman, Kurt, Young, Tracey, Cui, Wei, Huang, Zhiqing, Grenier, Carole, Wan, Ma, Stunnenberg, Hendrik G., Siscovick, David, Hou, Lifang, Psaty, Bruce M., Rich, Stephen S., Rotter, Jerome I., Kaufman, Joel D., Burke, Gregory L., Murphy, Susan, Jacobs, David R., Post, Wendy, Hoeschele, Ina, Bell, Douglas A., Herrington, David, Parks, John S., Tracy, Russell P., McCall, Charles E., Stein, James H.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2017
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5577184/
https://ncbi.nlm.nih.gov/pubmed/28855511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-00517-4
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