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Development of gene transfer for induction of antigen-specific tolerance

Gene replacement therapies, like organ and cell transplantation, are likely to introduce neoantigens that elicit rejection via humoral and/or effector T-cell immune responses. Nonetheless, thanks to an ever-growing body of preclinical studies; it is now well accepted that gene transfer protocols can...

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Pubblicato in:Mol Ther Methods Clin Dev
Autori principali: Sack, Brandon K, Herzog, Roland W, Terhorst, Cox, Markusic, David M
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4280786/
https://ncbi.nlm.nih.gov/pubmed/25558460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtm.2014.13
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