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In vivo Induction of Regulatory T Cells for Immune Tolerance in Hemophilia

Current therapy for the X-linked coagulation disorder hemophilia is based on intravenous infusion of the specifically deficient coagulation factor. However, 20–30% of hemophilia A patients (factor VIII, FVIII, deficiency) generate inhibitory antibodies against FVIII. Whilst formation of inhibitors d...

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Bibliographic Details
Published in:Cell Immunol
Main Authors: Wang, Xiaomei, Terhorst, Cox, Herzog, Roland W.
Format: Artigo
Language:Inglês
Published: 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4761281/
https://ncbi.nlm.nih.gov/pubmed/26454643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellimm.2015.10.001
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