Heat Stress Induces Apoptosis through a Ca(2+)-Mediated Mitochondrial Apoptotic Pathway in Human Umbilical Vein Endothelial Cells

BACKGROUND: Heat stress can be acutely cytotoxic, and heat stress-induced apoptosis is a prominent pathological feature of heat-related illnesses, although the precise mechanisms by which heat stress triggers apoptosis are poorly defined. METHODS: The percentages of viability and cell death were ass...

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Udgivet i:PLoS One
Main Authors: Li, Li, Tan, Hongping, Gu, Zhengtao, Liu, Zhifeng, Geng, Yan, Liu, Yunsong, Tong, Huasheng, Tang, Youqing, Qiu, Junmin, Su, Lei
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4280109/
https://ncbi.nlm.nih.gov/pubmed/25549352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0111083
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