Inhibition of porcine reproductive and respiratory syndrome virus infection by recombinant adenovirus- and/or exosome-delivered the artificial microRNAs targeting sialoadhesin and CD163 receptors

BACKGROUND: The current vaccines failed to provide substantial protection against porcine reproductive and respiratory syndrome (PRRS) and the new vaccine development faces great challenges. Sialoadhesin (Sn) and CD163 are the two key receptors for PRRS virus (PRRSV) infection of porcine alveolar ma...

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Bibliographic Details
Published in:Virol J
Main Authors: Zhu, Li, Song, Hongqin, Zhang, Xinyu, Xia, Xiaoli, Sun, Huaichang
Format: Artigo
Language:Inglês
Published: BioMed Central 2014
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4279792/
https://ncbi.nlm.nih.gov/pubmed/25522782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12985-014-0225-9
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