Inhibition of porcine reproductive and respiratory syndrome virus infection by recombinant adenovirus- and/or exosome-delivered the artificial microRNAs targeting sialoadhesin and CD163 receptors

BACKGROUND: The current vaccines failed to provide substantial protection against porcine reproductive and respiratory syndrome (PRRS) and the new vaccine development faces great challenges. Sialoadhesin (Sn) and CD163 are the two key receptors for PRRS virus (PRRSV) infection of porcine alveolar ma...

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Detalhes bibliográficos
Publicado no:Virol J
Main Authors: Zhu, Li, Song, Hongqin, Zhang, Xinyu, Xia, Xiaoli, Sun, Huaichang
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4279792/
https://ncbi.nlm.nih.gov/pubmed/25522782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12985-014-0225-9
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