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Induction of antibodies to the human immunodeficiency virus type 1 by immunization of baboons with immunoglobulin molecules carrying the principal neutralizing determinant of the envelope protein.

The hypervariable region 3 (V3) within the disulfide-bridged loop of the envelope protein of the human immunodeficiency virus type 1 (HIV-1) contains an amino acid sequence that was defined as a principal neutralizing determinant (PND). A 19-amino acid residue consensus sequence (designated V3C) pre...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Zaghouani, H, Anderson, S A, Sperber, K E, Daian, C, Kennedy, R C, Mayer, L, Bona, C A
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1995
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC42796/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7831341/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.2.631
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