Regulation of the viability of Nf1 deficient cells by PKC isoforms

Suppression of protein kinase C (PKC) is known to be synthetically lethal with ras mutations in various types of cancer cells. The studies also showed that blockade of PKC affected the viability of Nf1 deficient cells. Since PKC family consists of more than 10 isoforms, our study aimed at identifyin...

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Detalles Bibliográficos
Publicado en:Oncotarget
Autores principales: Zhou, Xiaodong, Shen, Ling, Parris, Toshima, Huang, Junchi, Yi, Bo, Helou, Khalil, Chen, Changyan
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4279404/
https://ncbi.nlm.nih.gov/pubmed/25301738
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