Regulation of the viability of Nf1 deficient cells by PKC isoforms

Suppression of protein kinase C (PKC) is known to be synthetically lethal with ras mutations in various types of cancer cells. The studies also showed that blockade of PKC affected the viability of Nf1 deficient cells. Since PKC family consists of more than 10 isoforms, our study aimed at identifyin...

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Vydáno v:Oncotarget
Hlavní autoři: Zhou, Xiaodong, Shen, Ling, Parris, Toshima, Huang, Junchi, Yi, Bo, Helou, Khalil, Chen, Changyan
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2014
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4279404/
https://ncbi.nlm.nih.gov/pubmed/25301738
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