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Thymidine phosphorylase activates NFκB and stimulates the expression of angiogenic and metastatic factors in human cancer cells

Thymidine phosphorylase (TP) promotes angiogenesis and metastasis, and confers resistance to anticancer agents in some cancer cell types. We previously reported that TP stimulates the expression of interleukin (IL)-8 in human KB cancer cells by an unknown mechanism. A mutation in the nuclear factor...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Tabata, Sho, Ikeda, Ryuji, Yamamoto, Masatatsu, Shimaoka, Shunji, Mukaida, Naofumi, Takeda, Yasuo, Yamada, Katsushi, Soga, Tomoyoshi, Furukawa, Tatsuhiko, Akiyama, Shin-ichi
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4279387/
https://ncbi.nlm.nih.gov/pubmed/25350954
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