WAVE binds Ena/VASP for enhanced Arp2/3 complex–based actin assembly

The WAVE complex is the main activator of the Arp2/3 complex for actin filament nucleation and assembly in the lamellipodia of moving cells. Other important players in lamellipodial protrusion are Ena/VASP proteins, which enhance actin filament elongation. Here we examine the molecular coordination...

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Vydáno v:Mol Biol Cell
Hlavní autoři: Havrylenko, Svitlana, Noguera, Philippe, Abou-Ghali, Majdouline, Manzi, John, Faqir, Fahima, Lamora, Audrey, Guérin, Christophe, Blanchoin, Laurent, Plastino, Julie
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Cell Biology 2015
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4279229/
https://ncbi.nlm.nih.gov/pubmed/25355952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E14-07-1200
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