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Capping protein is dispensable for polarized actin network growth and actin-based motility

Heterodimeric capping protein (CP) binds the rapidly growing barbed ends of actin filaments and prevents the addition (or loss) of subunits. Capping activity is generally considered to be essential for actin-based motility induced by Arp2/3 complex nucleation. By stopping barbed end growth, CP favor...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Abou-Ghali, Majdouline, Kusters, Remy, Körber, Sarah, Manzi, John, Faix, Jan, Sykes, Cécile, Plastino, Julie
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7650241/
https://ncbi.nlm.nih.gov/pubmed/32868296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.015009
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