Capping protein is dispensable for polarized actin network growth and actin-based motility

Heterodimeric capping protein (CP) binds the rapidly growing barbed ends of actin filaments and prevents the addition (or loss) of subunits. Capping activity is generally considered to be essential for actin-based motility induced by Arp2/3 complex nucleation. By stopping barbed end growth, CP favor...

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Vydáno v:J Biol Chem
Hlavní autoři: Abou-Ghali, Majdouline, Kusters, Remy, Körber, Sarah, Manzi, John, Faix, Jan, Sykes, Cécile, Plastino, Julie
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2020
Témata:
Cell Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7650241/
https://ncbi.nlm.nih.gov/pubmed/32868296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.015009
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