Capping protein is dispensable for polarized actin network growth and actin-based motility

Heterodimeric capping protein (CP) binds the rapidly growing barbed ends of actin filaments and prevents the addition (or loss) of subunits. Capping activity is generally considered to be essential for actin-based motility induced by Arp2/3 complex nucleation. By stopping barbed end growth, CP favor...

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Dades bibliogràfiques
Publicat a:J Biol Chem
Autors principals: Abou-Ghali, Majdouline, Kusters, Remy, Körber, Sarah, Manzi, John, Faix, Jan, Sykes, Cécile, Plastino, Julie
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2020
Matèries:
Cell Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7650241/
https://ncbi.nlm.nih.gov/pubmed/32868296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.015009
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