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A novel mechanism for the establishment of sister chromatid cohesion by the ECO1 acetyltransferase

Cohesin complex mediates cohesion between sister chromatids, which promotes high-fidelity chromosome segregation. Eco1p acetylates the cohesin subunit Smc3p during S phase to establish cohesion. The current model posits that this Eco1p-mediated acetylation promotes establishment by abrogating the ab...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Main Authors: Guacci, Vincent, Stricklin, Jeremiah, Bloom, Michelle S., Guō, Xuánzōng, Bhatter, Meghna, Koshland, Douglas
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4279223/
https://ncbi.nlm.nih.gov/pubmed/25378582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E14-08-1268
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