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A Direct Link between Sister Chromatid Cohesion and Chromosome Condensation Revealed through the Analysis of MCD1 in S. cerevisiae

The S. cerevisiae MCD1 (mitotic chromosome determinant) gene was identified in genetic screens for genes important for chromosome structure. MCD1 is essential for viability and homologs are found from yeast to humans. Analysis of the mcd1 mutant and cell cycle–dependent expression pattern of Mcd1p s...

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Detalhes bibliográficos
Main Authors: Guacci, Vincent, Koshland, Douglas, Strunnikov, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2670185/
https://ncbi.nlm.nih.gov/pubmed/9335334
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