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The zinc finger of Eco1 enhances its acetyltransferase activity during sister chromatid cohesion

Eco1p/Ctf7p is an essential acetyltransferase required for the establishment of sister chromatid cohesion. Eco1p acetylates Smc3p and Mcd1p (Scc1p or Rad21p) to establish cohesion during S phase and in response to DNA damage, respectively. In addition to its acetyltransferase domain, Eco1p harbors a...

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Autors principals: Onn, Itay, Guacci, Vincent, Koshland, Douglas E.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2764436/
https://ncbi.nlm.nih.gov/pubmed/19692582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp656
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