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The G Protein α Chaperone Ric-8 as a Potential Therapeutic Target

Resistance to inhibitors of cholinesterase (Ric-8)A and Ric-8B are essential genes that encode positive regulators of heterotrimeric G protein α subunits. Controversy persists surrounding the precise way(s) that Ric-8 proteins affect G protein biology and signaling. Ric-8 proteins chaperone nucleoti...

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Publicat a:Mol Pharmacol
Autors principals: Papasergi, Makaía M., Patel, Bharti R., Tall, Gregory G.
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Pharmacology and Experimental Therapeutics 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4279082/
https://ncbi.nlm.nih.gov/pubmed/25319541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.114.094664
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