A Novel Cryptic Binding Motif, LRSKSRSFQVSDEQY, in the C-Terminal Fragment of MMP-3/7-Cleaved Osteopontin as a Novel Ligand for α9β1 Integrin Is Involved in the Anti-Type II Collagen Antibody-Induced Arthritis

Osteopontin (OPN) is a multifunctional protein that has been linked to various intractable inflammatory diseases. One way by which OPN induces inflammation is the production of various functional fragments by enzyme cleavage. It has been well appreciated that OPN is cleaved by thrombin, and/or matri...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:PLoS One
Hlavní autoři: Kon, Shigeyuki, Nakayama, Yosuke, Matsumoto, Naoki, Ito, Koyu, Kanayama, Masashi, Kimura, Chiemi, Kouro, Hitomi, Ashitomi, Dai, Matsuda, Tadashi, Uede, Toshimitsu
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2014
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4278882/
https://ncbi.nlm.nih.gov/pubmed/25545242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0116210
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky