Essential role of the cryptic epitope SLAYGLR within osteopontin in a murine model of rheumatoid arthritis

It has been shown that osteopontin (OPN) plays a pivotal role in the pathogenesis of rheumatoid arthritis (RA). However, the molecular mechanism of OPN action is yet to be elucidated. Splenic monocytes obtained from arthritic mice exhibited a significant capacity for cell migration toward thrombin-c...

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Bibliografiske detaljer
Main Authors: Yamamoto, Nobuchika, Sakai, Fumihiko, Kon, Shigeyuki, Morimoto, Junko, Kimura, Chiemi, Yamazaki, Harumi, Okazaki, Ikuko, Seki, Nobuo, Fujii, Takashi, Uede, Toshimitsu
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2003
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC164290/
https://ncbi.nlm.nih.gov/pubmed/12865407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200317778
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