Syndecan-4 protects against osteopontin-mediated acute hepatic injury by masking functional domains of osteopontin

Osteopontin (OPN) is a T helper type 1 immunoregulatory cytokine that plays a critical role in various inflammatory disorders. OPN exerts proinflammatory reactions through interaction with integrin receptors. OPN function can be modulated by protease digestion. However, the molecular mechanisms that...

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Detalhes bibliográficos
Main Authors: Kon, Shigeyuki, Ikesue, Masahiro, Kimura, Chiemi, Aoki, Momoe, Nakayama, Yosuke, Saito, Yoshinari, Kurotaki, Daisuke, Diao, Hongyan, Matsui, Yutaka, Segawa, Tatsuya, Maeda, Masahiro, Kojima, Tetsuhito, Uede, Toshimitsu
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2008
Assuntos:
Brief Definitive Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2234375/
https://ncbi.nlm.nih.gov/pubmed/18158320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20071324
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