Syndecan-4 protects against osteopontin-mediated acute hepatic injury by masking functional domains of osteopontin

Osteopontin (OPN) is a T helper type 1 immunoregulatory cytokine that plays a critical role in various inflammatory disorders. OPN exerts proinflammatory reactions through interaction with integrin receptors. OPN function can be modulated by protease digestion. However, the molecular mechanisms that...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Kon, Shigeyuki, Ikesue, Masahiro, Kimura, Chiemi, Aoki, Momoe, Nakayama, Yosuke, Saito, Yoshinari, Kurotaki, Daisuke, Diao, Hongyan, Matsui, Yutaka, Segawa, Tatsuya, Maeda, Masahiro, Kojima, Tetsuhito, Uede, Toshimitsu
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Rockefeller University Press 2008
Pynciau:
Brief Definitive Reports
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2234375/
https://ncbi.nlm.nih.gov/pubmed/18158320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20071324
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