Structural evolution of glycan recognition by a family of potent HIV antibodies

The HIV envelope glycoprotein (Env) is densely covered with self-glycans that should help shield it from recognition by the human immune system. Here we examine how a particularly potent family of broadly neutralizing antibodies (Abs) has evolved common and distinct structural features to counter th...

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Détails bibliographiques
Publié dans:Cell
Auteurs principaux: Garces, Fernando, Sok, Devin, Kong, Leopold, McBride, Ryan, Kim, Helen J., Saye-Francisco, Karen F., Julien, Jean-Philippe, Hua, Yuanzi, Cupo, Albert, Moore, John P., Paulson, James C., Ward, Andrew B., Burton, Dennis R., Wilson, Ian A.
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4278586/
https://ncbi.nlm.nih.gov/pubmed/25259921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.09.009
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