Predictive biomarkers for dasatinib treatment in melanoma

Dasatinib has anti-proliferative and anti-invasive effects in melanoma cell lines. However clinical trials have shown modest activity for dasatinib in metastatic melanoma. Although dasatinib targets SRC kinase, neither expression nor phosphorylation of SRC appears to predict response to dasatinib. I...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Oncoscience
मुख्य लेखकों: Eustace, Alex J., Kennedy, Susan, Larkin, Anne-Marie, Mahgoub, Thamir, Tryfonopoulos, Dimitrios, O'Driscoll, Lorraine, Clynes, Martin, Crown, John, O'Donovan, Norma
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Impact Journals LLC 2014
विषय:
Research Paper
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4278284/
https://ncbi.nlm.nih.gov/pubmed/25594008
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