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The 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors, simvastatin, lovastatin and mevastatin inhibit proliferation and invasion of melanoma cells

BACKGROUND: A number of recent studies have suggested that cancer incidence rates may be lower in patients receiving statin treatment for hypercholesterolemia. We examined the effects of statin drugs on in vitro proliferation, migration and invasion of melanoma cells. METHODS: The ability of lovasta...

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Bibliografische gegevens
Hoofdauteurs: Glynn, Sharon A, O'Sullivan, Dermot, Eustace, Alex J, Clynes, Martin, O'Donovan, Norma
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2008
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2253545/
https://ncbi.nlm.nih.gov/pubmed/18199328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-8-9
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