The 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors, simvastatin, lovastatin and mevastatin inhibit proliferation and invasion of melanoma cells

BACKGROUND: A number of recent studies have suggested that cancer incidence rates may be lower in patients receiving statin treatment for hypercholesterolemia. We examined the effects of statin drugs on in vitro proliferation, migration and invasion of melanoma cells. METHODS: The ability of lovasta...

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Autores principales: Glynn, Sharon A, O'Sullivan, Dermot, Eustace, Alex J, Clynes, Martin, O'Donovan, Norma
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2008
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2253545/
https://ncbi.nlm.nih.gov/pubmed/18199328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-8-9
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