Overcoming EMT-driven therapeutic resistance by BH3 mimetics

Epithelial-mesenchymal transition (EMT) contributes to the progression of cancer through enhanced invasion and stem-like properties of cancer cells. Additionally, EMT confers resistance towards many chemotherapeutics. We recently described a mechanism that mediates EMT-driven chemoresistance through...

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Bibliographic Details
Published in:Oncoscience
Main Authors: Keitel, Ulrike, Scheel, Christina, Dobbelstein, Matthias
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2014
Subjects:
Research Perspective
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4278270/
https://ncbi.nlm.nih.gov/pubmed/25593997
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