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Impaired CD8(+) T cell immunity after allogeneic bone marrow transplantation leads to persistent and severe respiratory viral infection

RATIONALE: Bone marrow transplant (BMT) recipients experience frequent and severe respiratory viral infections (RVI). However, the immunological mechanisms predisposing to RVIs are uncertain. Therefore, we hypothesized that antiviral T cell immunity is impaired as a consequence of allogeneic BMT, in...

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Detalhes bibliográficos
Publicado no:Transpl Immunol
Main Authors: Gowdy, Kymberly M., Martinu, Tereza, Nugent, Julia L., Manzo, Nicholas D., Zhang, Helen, Kelly, Francine L., Holtzman, Michael J., Palmer, Scott M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4277946/
https://ncbi.nlm.nih.gov/pubmed/25446809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trim.2014.10.005
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