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Protective Role of T-bet and Th1 Cytokines in Pulmonary Graft-versus-Host Disease and Peribronchiolar Fibrosis

T-box expressed in T cells (T-bet) is a critical transcription factor for T helper (Th) 1 responses. Although Th1 cells are thought to contribute to certain alloimmune responses, their role in pulmonary graft-versus-host disease (GVHD) is uncertain. We have established a murine model of acute pulmon...

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Detalhes bibliográficos
Main Authors: Gowdy, Kymberly M., Nugent, Julia L., Martinu, Tereza, Potts, Erin, Snyder, Laurie D., Foster, W. Michael, Palmer, Scott M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3297167/
https://ncbi.nlm.nih.gov/pubmed/21960548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2011-0131OC
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