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Modest hyperglycemia prevents interstitial dispersion of insulin in skeletal muscle

Insulin injected directly into skeletal muscle diffuses rapidly through the interstitial space to cause glucose uptake, but this is blocked in insulin resistance. As glucotoxicity is associated with endothelial dysfunction, the observed hyperglycemia in diet-induced obese dogs may inhibit insulin ac...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Metabolism
मुख्य लेखकों: Kolka, Cathryn M., Castro, Ana Valeria B., Kirkman, Erlinda L., Bergman, Richard N.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2014
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4277905/
https://ncbi.nlm.nih.gov/pubmed/25468139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.metabol.2014.10.036
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