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Experimental Hyperlipidemia Dramatically Reduces Access of Insulin to Canine Skeletal Muscle

A complex sequence of steps is required for insulin to cause glucose uptake. Impairment of any one of these steps can contribute to insulin resistance. We observed the effect of insulin resistance induced by hyperlipidemia on the dynamics of insulin injected into skeletal muscle. Basal insulin eugly...

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Detalhes bibliográficos
Main Authors: Chiu, JD, Kolka, CM, Richey, JM, Harrison, LN, Zuniga, E, Kirkman, E, Bergman, RN
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3417110/
https://ncbi.nlm.nih.gov/pubmed/19521354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/oby.2009.165
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