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Diet-Induced Obesity Prevents Interstitial Dispersion of Insulin in Skeletal Muscle

OBJECTIVE: Obesity causes insulin resistance, which has been interpreted as reduced downstream insulin signaling. However, changes in access of insulin to sensitive tissues such as skeletal muscle may also play a role. Insulin injected directly into skeletal muscle diffuses rapidly through the inter...

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Detalhes bibliográficos
Main Authors: Kolka, Cathryn M., Harrison, L. Nicole, Lottati, Maya, Chiu, Jenny D., Kirkman, Erlinda L., Bergman, Richard N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2827487/
https://ncbi.nlm.nih.gov/pubmed/19959760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db09-0839
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