Sequential use of the androgen synthesis inhibitors ketoconazole and abiraterone acetate in castration-resistant prostate cancer and the predictive value of circulating androgens

PURPOSE: Patients previously treated with ketoconazole were excluded from phase III trials of abiraterone acetate due to potential overlapping mechanism of action. The purpose of this study was to determine the clinical utility of abiraterone and its impact on circulating androgens following ketocon...

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Bibliografiska uppgifter
I publikationen:Clin Cancer Res
Huvudupphovsmän: Kim, Won, Zhang, Li, Wilton, John H., Fetterly, Gerald, Mohler, James L., Weinberg, Vivian, Morse, Allison, Szmulewitz, Russell, Friedlander, Terence W., Fong, Lawrence, Lin, Amy M., Harzstark, Andrea, Molina, Arturo, Small, Eric J., Ryan, Charles J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2014
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4277885/
https://ncbi.nlm.nih.gov/pubmed/25336698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-14-1595
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