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Abiraterone Acetate: Targeting Persistent Androgen Dependence in Castration-Resistant Prostate Cancer
Abiraterone acetate is the first second-line hormonal agent proven to improve survival in metastatic castration-resistant prostate cancer. It selectively inhibits cytochrome P450 17 (CYP17) α-hydroxylase and cytochrome(17,20) (C(17,20))-lyase, which are enzymes critical for androgen synthesis. Abira...
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| 主要な著者: | , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Springer Healthcare
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3778906/ https://ncbi.nlm.nih.gov/pubmed/23979793 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12325-013-0050-3 |
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