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New cross-bridged cyclam derivative CB-TE1K1P, an improved bifunctional chelator for copper radionuclides()

A new cross-bridged cyclam chelator, CB-TE1K1P, was developed for copper-based radiopharmaceuticals, and this chelator can be labelled with (64)Cu under mild conditions in high specific activity. DBCO–PEG(4)–CB-TE1K1P was synthesized for conjugation to proteins, while Dde–CB-TE1K1P((t)Bu(2))–OH was...

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Bibliografiske detaljer
Udgivet i:Chem Commun (Camb)
Main Authors: Zeng, Dexing, Ouyang, Qin, Cai, Zhengxin, Xie, Xiang-Qun, Anderson, Carolyn J.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4277816/
https://ncbi.nlm.nih.gov/pubmed/24141371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c3cc45928d
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