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Manipulation of Endogenous Kinase Activity in Living Cells Using Photoswitchable Inhibitory Peptides
[Image: see text] Optogenetic control of endogenous signaling can be an important tool for probing cell behavior. Using the photoresponse of the LOV2 domain of Avena sativa phototropin 1, we developed analogues of kinase inhibitors whose activity is light dependent. Inhibitory peptides were appended...
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| Publicado no: | ACS Synth Biol |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Chemical
Society
2014
|
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4277778/ https://ncbi.nlm.nih.gov/pubmed/24905630 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/sb5001356 |
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