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Nickel-Catalyzed Negishi Arylations of Propargylic Bromides: A Mechanistic Investigation

[Image: see text] Although nickel-catalyzed stereoconvergent couplings of racemic alkyl electrophiles are emerging as a powerful tool in organic chemistry, to date there have been no systematic mechanistic studies of such processes. Herein, we examine the pathway for enantioselective Negishi arylati...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Schley, Nathan D., Fu, Gregory C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4277758/
https://ncbi.nlm.nih.gov/pubmed/25402209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja508718m
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