Synthesis and Preliminary Evaluation of a New (99m)Tc Labeled Substance P Analogue as a Potential Tumor Imaging Agent

Neurokinin 1 receptors (NK(1)R) are overexpressed on several types of important human cancer cells. Substance P (SP) is the most specific endogenous ligand known for NK(1)Rs. Accordingly,a new SP analogue was synthesized and evaluated for detection of NK(1)R positive tumors.[6-hydrazinopyridine-3-ca...

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Detalhes bibliográficos
Publicado no:Iran J Pharm Res
Main Authors: Mozaffari, Saeed, Erfani, Mostafa, Beiki, Davood, Johari Daha, Fariba, Kobarfard, Farzad, Balalaie, Saeed, Fallahi, Babak
Formato: Artigo
Idioma:Inglês
Publicado em: Shaheed Beheshti University of Medical Sciences 2015
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4277623/
https://ncbi.nlm.nih.gov/pubmed/25561916
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