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Synthesis and Preliminary Evaluation of a New (99m)Tc Labeled Substance P Analogue as a Potential Tumor Imaging Agent
Neurokinin 1 receptors (NK(1)R) are overexpressed on several types of important human cancer cells. Substance P (SP) is the most specific endogenous ligand known for NK(1)Rs. Accordingly,a new SP analogue was synthesized and evaluated for detection of NK(1)R positive tumors.[6-hydrazinopyridine-3-ca...
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| Publicat a: | Iran J Pharm Res |
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| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Shaheed Beheshti University of Medical Sciences
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4277623/ https://ncbi.nlm.nih.gov/pubmed/25561916 |
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