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A (99m)Tc-tricine-HYNIC-labeled Peptide Targeting the Melanocortin-1 Receptor for Melanoma Imaging
Melanocortin-1 (MC1) receptor is an attractive melanoma-specific target for the development of α-MSH peptide based imaging and therapeutic agents. In this work a new lactam bridge α-MSH analogue was synthesized and radiolabeled with (99m)Tc via HYNIC chelator and tricine as co-ligand. Also, stabilit...
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Publicado no: | Iran J Pharm Res |
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Main Authors: | , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Shaheed Beheshti University of Medical Sciences
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5149022/ https://ncbi.nlm.nih.gov/pubmed/27980570 |
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