Increasing Secretion of a Bivalent Anti-T-Cell Immunotoxin by Pichia pastoris

The bivalent anti-T-cell immunotoxin A-dmDT390-bisFv(G(4)S) was developed for treatment of T-cell leukemia and autoimmune diseases and for tolerance induction for transplantation. This immunotoxin was produced extracellularly in toxin-sensitive Pichia pastoris JW102 (Mut(+)) under control of the AOX...

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-д хэвлэсэн:	Appl Environ Microbiol
Үндсэн зохиолчид:	Woo, Jung Hee, Liu, Yuan Yi, Stavrou, Scott, Neville, David M.
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	American Society for Microbiology (ASM) 2004
Нөхцлүүд:	Physiology and Biotechnology
Онлайн хандалт:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC427749/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15184133/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AEM.70.6.3370-3376.2004
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