Increasing Secretion of a Bivalent Anti-T-Cell Immunotoxin by Pichia pastoris
The bivalent anti-T-cell immunotoxin A-dmDT390-bisFv(G(4)S) was developed for treatment of T-cell leukemia and autoimmune diseases and for tolerance induction for transplantation. This immunotoxin was produced extracellularly in toxin-sensitive Pichia pastoris JW102 (Mut(+)) under control of the AOX...
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| Publicado no: | Appl Environ Microbiol |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC427749/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15184133/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AEM.70.6.3370-3376.2004 |
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