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Interactions between RNA polymerase and the “core recognition element” counteract pausing

Transcription elongation is interrupted by sequences that inhibit nucleotide addition and cause RNA polymerase (RNAP) to pause. Here, by use of native-elongating-transcript sequencing (NET-seq) and a variant of NET-seq that enables analysis of mutant RNAP derivatives in merodiploid cells (mNET-seq),...

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Bibliografske podrobnosti
izdano v:Science
Main Authors: Vvedenskaya, Irina O., Vahedian-Movahed, Hanif, Bird, Jeremy G., Knoblauch, Jared G., Goldman, Seth R., Zhang, Yu, Ebright, Richard H., Nickels, Bryce E.
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4277259/
https://ncbi.nlm.nih.gov/pubmed/24926020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1253458
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