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Robust and precise morphogen-mediated patterning: trade-offs, constraints and mechanisms

The patterning of many developing tissues is organized by morphogens. Genetic and environmental perturbations of gene expression, protein synthesis and ligand binding are among the sources of unreliability that limit the accuracy and precision of morphogen-mediated patterning. While it has been foun...

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Bibliografiska uppgifter
I publikationen:J R Soc Interface
Huvudupphovsmän: Lo, Wing-Cheong, Zhou, Shaohua, Wan, Frederic Y.-M., Lander, Arthur D., Nie, Qing
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Royal Society 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4277094/
https://ncbi.nlm.nih.gov/pubmed/25551154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2014.1041
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